GADD45GIP1

Across TCGA cell cohorts, GADD45GIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,349 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GADD45GIP1-associated GO terms across cancer lineages are rRNA pseudouridine synthesis, Enzyme-directed rRNA pseudouridine synthesis, and Protein localization to microtubule plus-end. Each is linked with GADD45GIP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both GADD45GIP1-to-partner and partner-to-GADD45GIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA pseudouridine synthesis grouped by GADD45GIP1-low versus GADD45GIP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GADD45GIP1→partner) and Y-score (partner→GADD45GIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	rRNA pseudouridine synthesis →	+0.137	+0.833	<.001	<.001	3	13
LUNG_SCLC	Enzyme-directed rRNA pseudouridine synthesis →	+0.104	+0.599	.002	.004	3	13
SKIN	Protein localization to microtubule plus-end →	+0.241	+1.099	<.001	<.001	3	12
SKIN	Protein localization to microtubule end →	+0.241	+1.099	<.001	<.001	3	12
BLOOD_Myeloma	[4Fe-4S] cluster assembly →	+0.175	+1.134	<.001	<.001	3	12
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.164	+1.125	.003	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,349 associations by consensus.

rRNA pseudouridine synthesis by GADD45GIP1 expression — OESOPHAGUS

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