GABRR3

Across TCGA pan-cancer cohorts, GABRR3 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated GABRR3 data layer compared with 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GABRR3 RNA is associated with better overall survival. In most high-consensus cancer types, elevated GABRR3 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CESC show a favorable association.

LUAD, KIRC, and KICH are the cancer types where GABRR3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.687	0.471	<.001	92	view →
KIRC	DFS	Tertile	III,IV	0.297	0.536	<.001	81	view →
KICH	OS	Quartile	All	0.597	1.000	<.001	67	view →
DLBC	DFS	Quartile	All	0.114	0.984	<.001	58	view →
KIRP	OS	Tertile	All	0.561	0.738	<.001	53	view →
CESC	DFS	Tertile	III,IV	1.000	0.636	.002	48	view →
UVM	DFS	Median	All	0.451	0.895	<.001	41	view →
LIHC	OS	Median	All	0.469	0.645	.002	39	view →
BRCA	OS	Median	III,IV	0.749	0.880	.002	29	view →
THCA	OS	Quartile	All	0.667	0.948	<.001	25	view →
UCS	OS	Quartile	III,IV	1.000	0.284	.018	18	view →
CHOL	OS	Quartile	III,IV	0.024	0.839	.025	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

GABRR3–LUAD (OS)

Open the LUAD breakdown →