GABRR2

Across TCGA cell cohorts, GABRR2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GABRR2-associated genes across cancer lineages are C9orf92, SLC5A8, and LCE2A. Each is linked with GABRR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRR2-to-partner and partner-to-GABRR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf92 grouped by GABRR2-low versus GABRR2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRR2→partner) and Y-score (partner→GABRR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C9orf92 →	+0.194	+5.369	<.001	.004	3	1
SOFT_TISSUE	SLC5A8 →	+0.006	+4.930	<.001	.008	3	1
BLOOD_Leukemia	LCE2A →	+0.053	+4.969	<.001	.003	3	1
BLOOD_Leukemia	VWC2 →	+0.394	+4.551	.002	.004	3	1
LARGE_INTESTINE	C10orf53 →	+0.019	+4.217	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

C9orf92 by GABRR2 expression — SOFT_TISSUE

Explore this box plot interactively →