GABRR1

Across TCGA pan-cancer cohorts, GABRR1 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GABRR1 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher GABRR1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GABRR1 expression acts as an unfavorable survival marker.

THYM, LUSC, and MESO are the cancer types where GABRR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
LUSC	OS	Median	III,IV	0.011	0.684	<.001	12	view →
MESO	DFS	Median	III,IV	0.078	0.376	.012	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LGG	DFS	Median	All	0.225	0.728	.029	3	view →
SKCM	OS	Median	All	0.210	0.781	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GABRR1–THYM (OS)

Open the THYM breakdown →