GABRR1

Across TCGA patient cohorts, GABRR1 mutation is significantly associated with the RNA expression of many other genes, with 2,173 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABRR1-associated genes across cancer lineages are RNU7-90P, MIA-RAB4B, and RNA5SP162. Each is linked with GABRR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GABRR1-to-partner and partner-to-GABRR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-90P grouped by GABRR1-low versus GABRR1-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRR1→partner) and Y-score (partner→GABRR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	RNU7-90P →	+0.550	+5.813	<.001	<.001	3	3
UCEC	MIA-RAB4B →	+0.097	+2.670	<.001	<.001	3	3
CESC	RNA5SP162 →	+0.771	+5.103	<.001	.008	3	2
CESC	NF1P10 →	+0.235	+6.569	<.001	.001	3	2
SARC	PGBD4P4 →	+0.082	+5.392	<.001	.001	3	2
SARC	RN7SL353P →	+0.257	+3.836	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,173 associations by consensus.

RNU7-90P by GABRR1 expression — SARC

Explore this box plot interactively →