GABRQ

Across TCGA pan-cancer cohorts, GABRQ Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GABRQ data layer compared with 25 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GABRQ Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated GABRQ expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

UCEC, KIRP, and OV are the cancer types where GABRQ Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.946	0.618	.004	32	view →
KIRP	DFS	Median	All	0.037	0.920	<.001	24	view →
OV	OS	Median	III,IV	0.076	0.837	<.001	24	view →
HNSC	OS	Median	II,III,IV	0.086	0.711	<.001	23	view →
LIHC	OS	Median	II,III,IV	0.092	0.716	<.001	21	view →
LUAD	OS	Median	All	0.443	0.677	.047	2	view →
BLCA	OS	Median	IV	1.000	0.250	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GABRQ–UCEC (DFS)

Open the UCEC breakdown →