GABRG2

Across TCGA patient cohorts, GABRG2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,289 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GABRG2-associated genes across cancer lineages are PRODH, GRK3, and SOX10. Each is linked with GABRG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRG2-to-partner and partner-to-GABRG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABRG2 versus PRODH in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRG2→partner) and Y-score (partner→GABRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+1.101	+0.548	<.001	<.001	3	1
GBM	GRK3 →	+0.426	+0.486	.007	.005	3	1
GBM	SOX10 →	+1.329	+0.582	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.239	+0.697	<.001	<.001	3	1
GBM	CYP2D6 →	+0.471	+0.413	.007	.002	3	1
GBM	SUN2 →	+0.369	+0.432	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,289 associations by consensus.

GABRG2 vs PRODH — GBM

Explore this scatter interactively →