Across TCGA patient cohorts, GABRD protein abundance is significantly associated with the RNA expression of many other genes, with 1,040 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GABRD-associated genes across cancer lineages are NEFH, HMOX1, and RASD2. Each is linked with GABRD in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRD-to-partner and partner-to-GABRD results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRD→partner) and Y-score (partner→GABRD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NEFH →	+1.517	+1.071	<.001	<.001	3	1
GBM	HMOX1 →	-1.298	-0.995	.006	.004	3	1
GBM	RASD2 →	+0.921	+1.153	.002	.002	3	1
GBM	SYNGR1 →	+1.035	+1.102	<.001	<.001	3	1
GBM	PNPLA5 →	+0.389	+1.129	<.001	<.001	3	1
GBM	CACNA1I →	+0.917	+1.115	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,040 associations by consensus.

Exploration

GABRD survival (RNA) · tumor vs normal (RNA) · all GABRD data types