Across TCGA cell cohorts, GABRD RNA expression is significantly associated with the go_rna of many other GO terms, with 2,653 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GABRD-associated GO terms across cancer lineages are Negative regulation of glucagon secretion, Fat cell proliferation, and Primary alcohol biosynthetic process. Each is linked with GABRD in more than 8 cancer types. Because this analysis shows association rather than direction, both GABRD-to-partner and partner-to-GABRD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRD→partner) and Y-score (partner→GABRD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of glucagon secretion →	+0.992	+0.189	<.001	.007	3	9
LUNG_SCLC	Fat cell proliferation →	-0.378	-1.498	.001	.001	3	9
KIDNEY	Primary alcohol biosynthetic process →	-0.274	-0.349	<.001	.007	3	9
SOFT_TISSUE	Regulation of calcium ion transport into cytosol →	-0.293	-1.140	<.001	<.001	3	8
OESOPHAGUS	Cell fate commitment →	-0.054	-1.162	.001	.007	3	8
BONE	Pancreas development →	-0.098	-1.300	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,653 associations by consensus.

Exploration

GABRD survival (RNA) · tumor vs normal (RNA) · all GABRD data types