GABRB3

Across TCGA patient cohorts, GABRB3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,231 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GABRB3-associated genes across cancer lineages are YPEL1, GRK3, and SOX10. Each is linked with GABRB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRB3-to-partner and partner-to-GABRB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABRB3 versus YPEL1 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRB3→partner) and Y-score (partner→GABRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YPEL1 →	+0.644	+0.460	<.001	<.001	3	1
GBM	GRK3 →	+0.378	+0.372	<.001	<.001	3	1
GBM	SOX10 →	+1.278	+0.383	.002	.001	3	1
GBM	SLC16A8 →	+0.481	+0.310	.002	.002	3	1
GBM	SEPTIN3 →	+1.824	+0.650	<.001	<.001	3	1
GBM	RASL10A →	+0.743	+0.463	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,231 associations by consensus.

GABRB3 vs YPEL1 — GBM

Explore this scatter interactively →