GABRB2

Across TCGA patient cohorts, GABRB2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,473 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GABRB2-associated genes across cancer lineages are PRODH, SOX10, and SEPTIN3. Each is linked with GABRB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRB2-to-partner and partner-to-GABRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABRB2 versus PRODH in GBM, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRB2→partner) and Y-score (partner→GABRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.553	+0.565	.008	<.001	3	1
GBM	SOX10 →	+1.211	+0.615	.003	<.001	3	1
GBM	SEPTIN3 →	+1.040	+0.665	.001	.001	3	1
GBM	SLC5A4 →	+0.512	+0.543	<.001	.002	3	1
GBM	CYP2D6 →	+0.451	+0.675	.002	<.001	3	1
GBM	NEFH →	+1.018	+0.610	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,473 associations by consensus.

GABRB2 vs PRODH — GBM

Explore this scatter interactively →