GABRB2

Across TCGA patient cohorts, GABRB2 mutation is significantly associated with the RNA expression of many other genes, with 6,709 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABRB2-associated genes across cancer lineages are MIR6784, RNU6-4P, and PTS. Each is linked with GABRB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GABRB2-to-partner and partner-to-GABRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6784 grouped by GABRB2-low versus GABRB2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRB2→partner) and Y-score (partner→GABRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6784 →	+0.407	+1.245	.004	.002	3	3
LUSC	RNU6-4P →	+0.379	+2.643	.003	.003	3	3
UCEC	PTS →	+0.326	+3.606	<.001	<.001	3	3
UCEC	LAIR2 →	+0.386	+1.312	<.001	<.001	3	3
UCEC	SNX24 →	+0.323	+1.584	<.001	.001	3	3
UCEC	TTC1 →	+0.277	+1.568	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,709 associations by consensus.

MIR6784 by GABRB2 expression — UCEC

Explore this box plot interactively →