GABRB2

Across TCGA cell cohorts, GABRB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,469 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GABRB2-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Inhibitory synapse assembly, and Aerobic electron transport chain. Each is linked with GABRB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GABRB2-to-partner and partner-to-GABRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by GABRB2-low versus GABRB2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRB2→partner) and Y-score (partner→GABRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of double-strand break repair via homologous recombination →	+0.080	+0.619	<.001	.001	3	5
BLOOD_Lymphoma	Inhibitory synapse assembly →	-0.111	-0.591	<.001	<.001	3	4
BLOOD_Leukemia	Aerobic electron transport chain →	+0.055	+0.450	<.001	<.001	3	4
LUNG_SCLC	Respiratory electron transport chain →	+0.098	+1.403	<.001	<.001	3	4
BLOOD_Leukemia	Regulation of synaptic transmission, GABAergic →	-0.085	-0.518	<.001	.002	3	4
BLOOD_Leukemia	ATP synthesis coupled electron transport →	+0.056	+0.450	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,469 associations by consensus.

Regulation of double-strand break repair via homologous recombination by GABRB2 expression — BLOOD_Lymphoma

Explore this box plot interactively →