GABRA2

Across TCGA cell cohorts, GABRA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,088 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GABRA2-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, Nucleic acid catabolic process, and Negative regulation of chromosome condensation. Each is linked with GABRA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GABRA2-to-partner and partner-to-GABRA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase II promoter grouped by GABRA2-low versus GABRA2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRA2→partner) and Y-score (partner→GABRA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription initiation at RNA polymerase II promoter →	+0.074	+0.986	.001	.002	3	6
BONE	Nucleic acid catabolic process →	+0.053	+1.079	.002	.001	3	5
BONE	Negative regulation of chromosome condensation →	+0.119	+1.240	<.001	<.001	3	5
BONE	Regulation of telomerase RNA localization to Cajal body →	+0.117	+1.222	.001	.006	3	5
BONE	Positive regulation of double-strand break repair via homologous recombination →	+0.086	+1.147	<.001	.002	3	5
BONE	Epigenetic regulation of gene expression →	+0.065	+1.053	.003	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,088 associations by consensus.

Transcription initiation at RNA polymerase II promoter by GABRA2 expression — BONE

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