GABPB2

Across TCGA cell cohorts, GABPB2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GABPB2-associated genes across cancer lineages are MDGA2, MCHR2, and P2RY12. Each is linked with GABPB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABPB2-to-partner and partner-to-GABPB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MDGA2 grouped by GABPB2-low versus GABPB2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABPB2→partner) and Y-score (partner→GABPB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MDGA2 →	+0.172	+3.854	<.001	.006	3	1
LARGE_INTESTINE	MCHR2 →	+0.019	+5.099	.001	<.001	3	1
LARGE_INTESTINE	P2RY12 →	+0.238	+4.688	<.001	<.001	3	1
LARGE_INTESTINE	RTP1 →	+0.234	+3.930	<.001	.003	3	1
LARGE_INTESTINE	EIF4E1B →	+0.170	+4.029	<.001	.004	3	1
LARGE_INTESTINE	MAGEB10 →	+0.089	+5.345	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MDGA2 by GABPB2 expression — LARGE_INTESTINE

Explore this box plot interactively →