GABPB1

Across TCGA patient cohorts, GABPB1 mutation is significantly associated with the RNA expression of many other genes, with 4,403 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABPB1-associated genes across cancer lineages are SPRING1P1, RNU4-56P, and HSPD1P14. Each is linked with GABPB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GABPB1-to-partner and partner-to-GABPB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPRING1P1 grouped by GABPB1-low versus GABPB1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABPB1→partner) and Y-score (partner→GABPB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SPRING1P1 →	+0.046	+4.797	<.001	.003	3	4
LIHC	RNU4-56P →	+0.247	+5.186	<.001	.007	3	2
SKCM	HSPD1P14 →	+0.013	+4.328	<.001	.007	3	2
UCEC	MIR4452 →	+0.141	+2.818	<.001	.008	3	2
UCEC	RNU1-57P →	+0.121	+3.411	<.001	.002	3	2
UCEC	TCERG1L-AS1 →	+0.305	+2.117	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,403 associations by consensus.

SPRING1P1 by GABPB1 expression — SKCM

Explore this box plot interactively →