GABPB1

Across TCGA cell cohorts, GABPB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,960 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GABPB1-associated GO terms across cancer lineages are Protein localization to kinetochore, Spindle assembly, and Mitotic sister chromatid cohesion. Each is linked with GABPB1 in more than 17 cancer types. Because this analysis shows association rather than direction, both GABPB1-to-partner and partner-to-GABPB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to kinetochore grouped by GABPB1-low versus GABPB1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABPB1→partner) and Y-score (partner→GABPB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein localization to kinetochore →	+0.199	+0.529	.002	.006	3	18
UPPER_AERODIGESTIVE_TRACT	Spindle assembly →	+0.078	+0.634	.001	.001	3	16
BLOOD_Myeloma	Mitotic sister chromatid cohesion →	+0.097	+0.935	<.001	<.001	3	16
CNS	Sister chromatid segregation →	+0.096	+0.555	<.001	<.001	3	16
URINARY_TRACT	Regulation of cell cycle checkpoint →	+0.108	+0.770	.001	<.001	3	16
BONE	Negative regulation of cell cycle phase transition →	+0.088	+0.646	.005	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,960 associations by consensus.

Protein localization to kinetochore by GABPB1 expression — BONE

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