GABPB1

Across TCGA cell cohorts, GABPB1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GABPB1-associated genes across cancer lineages are OR6Q1, C9orf57, and PPEF2. Each is linked with GABPB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABPB1-to-partner and partner-to-GABPB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6Q1 grouped by GABPB1-low versus GABPB1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABPB1→partner) and Y-score (partner→GABPB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR6Q1 →	+0.018	+4.437	<.001	.004	3	1
SKIN	C9orf57 →	+0.014	+4.415	<.001	.007	3	1
LARGE_INTESTINE	PPEF2 →	+0.050	+3.736	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR6Q1 by GABPB1 expression — LARGE_INTESTINE

Explore this box plot interactively →