GABPB1-AS1

Across TCGA pan-cancer cohorts, GABPB1-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of GABPB1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where GABPB1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GABPB1-AS1 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

COAD, LIHC, and HNSC are the cancer types where GABPB1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GABPB1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.706	<.001	10	view →
LIHC	Female	All	+0.426	<.001	7	view →
HNSC	All	III,IV	+0.315	.003	7	view →
BRCA	Female	II,III,IV	−0.575	<.001	6	view →
STAD	All	All	+0.563	.005	4	view →
THCA	All	All	−0.428	.002	4	view →
READ	All	All	+1.128	<.001	3	view →
KICH	Female	All	−0.668	.001	3	view →
CHOL	All	All	+1.580	<.001	2	view →
BLCA	All	All	+0.560	.040	2	view →
PRAD	All	All	+0.427	.002	2	view →
LUSC	All	All	+0.346	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

GABPB1-AS1–COAD

Open the COAD breakdown →