GABPA

Across TCGA patient cohorts, GABPA protein abundance is significantly associated with the RNA expression of many other genes, with 16,908 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GABPA-associated genes across cancer lineages are ZBTB12, CEP68, and KLF12. Each is linked with GABPA in more than 7 cancer types. Because this analysis shows association rather than direction, both GABPA-to-partner and partner-to-GABPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABPA versus ZBTB12 in HNSC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABPA→partner) and Y-score (partner→GABPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZBTB12 →	+0.657	+0.237	<.001	<.001	3	8
HNSC	CEP68 →	+0.467	+0.185	<.001	<.001	3	7
UCEC	KLF12 →	+0.913	+0.170	.001	.003	3	7
LSCC	XPA →	+0.794	+0.290	<.001	<.001	3	7
LUAD	CXCL8 →	-1.886	-0.173	<.001	<.001	3	7
HNSC	ZNF37BP →	+0.519	+0.202	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,908 associations by consensus.

GABPA vs ZBTB12 — HNSC

Explore this scatter interactively →