GABPA

Across TCGA cell cohorts, GABPA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,883 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GABPA-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Monoubiquitinated protein deubiquitination, and Phosphatidylinositol-3-phosphate biosynthetic process. Each is linked with GABPA in more than 16 cancer types. Because this analysis shows association rather than direction, both GABPA-to-partner and partner-to-GABPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by GABPA-low versus GABPA-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABPA→partner) and Y-score (partner→GABPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair →	+0.081	+0.955	<.001	<.001	3	17
LIVER	Monoubiquitinated protein deubiquitination →	+0.158	+0.534	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.078	+0.791	<.001	.001	3	16
BONE	Protein desumoylation →	+0.105	+1.016	<.001	<.001	3	15
SOFT_TISSUE	Positive regulation of organelle assembly →	+0.056	+0.646	.001	.001	3	15
BONE	Positive regulation of DNA repair →	+0.068	+0.706	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,883 associations by consensus.

Positive regulation of double-strand break repair by GABPA expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →