GABBR2

Across TCGA patient cohorts, GABBR2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,440 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GABBR2-associated genes across cancer lineages are UPB1, YPEL1, and SNRPD3. Each is linked with GABBR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABBR2-to-partner and partner-to-GABBR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABBR2 versus UPB1 in GBM, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABBR2→partner) and Y-score (partner→GABBR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	UPB1 →	+0.153	+0.438	.002	.004	3	1
GBM	YPEL1 →	+0.466	+0.579	.005	.001	3	1
GBM	SNRPD3 →	+0.346	+0.396	<.001	.002	3	1
GBM	PRODH →	+0.807	+0.538	<.001	<.001	3	1
GBM	GRK3 →	+0.498	+0.646	<.001	<.001	3	1
GBM	SEZ6L →	+1.356	+0.524	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,440 associations by consensus.

GABBR2 vs UPB1 — GBM

Explore this scatter interactively →