GABBR2

Across TCGA cell cohorts, GABBR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,161 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GABBR2-associated GO terms across cancer lineages are Actin filament fragmentation, Vesicle cargo loading, and Negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. Each is linked with GABBR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GABBR2-to-partner and partner-to-GABBR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament fragmentation grouped by GABBR2-low versus GABBR2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABBR2→partner) and Y-score (partner→GABBR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Actin filament fragmentation →	+0.110	+2.513	.003	<.001	3	6
CNS	Vesicle cargo loading →	+0.080	+0.982	<.001	.003	3	5
STOMACH	Negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway →	+0.152	+1.259	<.001	.006	3	5
URINARY_TRACT	Cilium disassembly →	+0.138	+2.173	.002	<.001	3	5
BONE	Protein folding →	+0.069	+0.875	<.001	.004	3	5
BREAST	Endosome organization →	+0.043	+0.671	.003	.009	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,161 associations by consensus.

Actin filament fragmentation by GABBR2 expression — LUNG_SCLC

Explore this box plot interactively →