Across TCGA patient cohorts, GABBR1 mutation is significantly associated with the total protein of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GABBR1-associated genes across cancer lineages are ASNS, 4E-BP1, and PCNA. Each is linked with GABBR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GABBR1-to-partner and partner-to-GABBR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABBR1→partner) and Y-score (partner→GABBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ASNS →	+0.695	+3.169	<.001	.018	3	4
STAD	4E-BP1 →	+0.557	+3.584	<.001	.002	2	4
COAD	PCNA →	+0.249	+2.178	.032	.035	3	3
UCEC	c-Met_pY1235 →	+0.070	+1.764	.001	<.001	3	3
STAD	eIF4E →	+0.237	+2.828	.002	.033	3	2
STAD	GSK3-a-b →	+0.191	+2.480	.007	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

Exploration

GABBR1 survival (RNA) · tumor vs normal (RNA) · all GABBR1 data types