Across TCGA cell cohorts, GABBR1 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GABBR1-associated genes across cancer lineages are OR4X2, LCE6A, and TMEM95. Each is linked with GABBR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABBR1-to-partner and partner-to-GABBR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABBR1→partner) and Y-score (partner→GABBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR4X2 →	+0.013	+4.369	.006	.008	3	1
SOFT_TISSUE	LCE6A →	+0.030	+4.977	<.001	.002	3	1
LUNG_SCLC	TMEM95 →	+0.049	+5.029	<.001	.006	3	1
BLOOD_Lymphoma	DEFB129 →	+0.026	+4.662	<.001	.003	3	1
BLOOD_Lymphoma	KRT71 →	+0.007	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	FCN3 →	+0.047	+3.954	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

Exploration

GABBR1 survival (RNA) · tumor vs normal (RNA) · all GABBR1 data types