GABARAP

Across TCGA patient cohorts, GABARAP protein abundance is significantly associated with the RNA expression of many other genes, with 9,377 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GABARAP-associated genes across cancer lineages are SAMD12-AS1, KLHL11, and YAE1. Each is linked with GABARAP in more than 3 cancer types. Because this analysis shows association rather than direction, both GABARAP-to-partner and partner-to-GABARAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABARAP versus SAMD12-AS1 in LSCC, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABARAP→partner) and Y-score (partner→GABARAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SAMD12-AS1 →	-1.023	-0.285	<.001	<.001	3	4
LSCC	KLHL11 →	-0.496	-0.255	<.001	<.001	3	4
COAD	YAE1 →	-0.584	-0.285	.003	<.001	2	4
COAD	POFUT1 →	-0.980	-0.310	<.001	<.001	3	3
LSCC	IFNG →	+1.078	+0.397	<.001	<.001	3	3
LSCC	BCHE →	-1.295	-0.373	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,377 associations by consensus.

GABARAP vs SAMD12-AS1 — LSCC

Explore this scatter interactively →