Across TCGA patient cohorts, GAB4 RNA expression is significantly associated with the protein abundance of many other proteins, with 1,467 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GAB4-associated proteins across cancer lineages are TEX264, SLC9A3R1, and CRISP3. Each is linked with GAB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAB4-to-partner and partner-to-GAB4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GAB4→partner) and Y-score (partner→GAB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TEX264 →	-0.203	-0.424	.008	.005	3	2
BRCA	SLC9A3R1 →	-0.554	-0.046	<.001	.009	3	2
BRCA	CRISP3 →	+0.624	+0.029	.007	.002	3	2
BRCA	DENND2D →	-0.478	-0.038	<.001	.004	3	2
BRCA	DGCR8_T371 →	+0.820	+0.040	.007	.002	3	2
BRCA	GOLGA5 →	-0.344	-0.031	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,467 associations by consensus.

Exploration

GAB4 survival (RNA) · tumor vs normal (RNA) · all GAB4 data types