GAB3

Across TCGA patient cohorts, GAB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,757 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GAB3-associated proteins across cancer lineages are STK10, ARHGEF6_S225, and PTPN7. Each is linked with GAB3 in more than 9 cancer types. Because this analysis shows association rather than direction, both GAB3-to-partner and partner-to-GAB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAB3 versus STK10 in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GAB3→partner) and Y-score (partner→GAB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STK10 →	+0.439	+0.793	<.001	<.001	3	10
OV	ARHGEF6_S225 →	+0.799	+1.095	<.001	<.001	3	10
OV	PTPN7 →	+0.623	+0.702	<.001	.002	3	10
OV	RASAL3 →	+0.673	+1.063	<.001	<.001	3	10
OV	RASSF2 →	+0.560	+0.983	.001	<.001	3	10
HNSC	RCSD1 →	+0.651	+0.821	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,757 associations by consensus.

GAB3 vs STK10 — LSCC

Explore this scatter interactively →