GAB3

Across TCGA patient cohorts, GAB3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,241 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GAB3-associated genes across cancer lineages are MFNG, PPP1R16B, and TLR8. Each is linked with GAB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GAB3-to-partner and partner-to-GAB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAB3 versus MFNG in BRCA, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAB3→partner) and Y-score (partner→GAB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MFNG →	+1.088	+0.750	.004	.004	3	3
BRCA	PPP1R16B →	+1.116	+0.645	.001	.003	3	3
BRCA	TLR8 →	+1.301	+0.904	.004	.001	3	3
BRCA	RASAL3 →	+1.035	+0.630	.006	.004	3	3
BRCA	VSIR →	+0.964	+0.593	.008	.003	3	3
BRCA	GZMK →	+1.647	+0.621	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,241 associations by consensus.

GAB3 vs MFNG — BRCA

Explore this scatter interactively →