GAB2

Across TCGA patient cohorts, GAB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,364 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAB2-associated proteins across cancer lineages are SORBS1, DDAH2, and GAB2_S223. Each is linked with GAB2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GAB2-to-partner and partner-to-GAB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAB2 versus SORBS1 in UCEC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GAB2→partner) and Y-score (partner→GAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SORBS1 →	+0.664	+0.403	<.001	<.001	3	6
LSCC	DDAH2 →	+0.335	+0.679	<.001	<.001	3	6
UCEC	GAB2_S223 →	+0.993	+0.840	<.001	<.001	3	6
OV	PLCL1 →	+0.683	+1.335	.002	.001	3	6
HNSC	RPS2 →	-0.190	-0.467	<.001	<.001	3	5
UCEC	AGO1 →	+0.339	+0.410	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,364 associations by consensus.

GAB2 vs SORBS1 — UCEC

Explore this scatter interactively →