GAB1

Across TCGA patient cohorts, GAB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,994 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GAB1-associated proteins across cancer lineages are RBSN, MYO1D, and DDX21_S89. Each is linked with GAB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GAB1-to-partner and partner-to-GAB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAB1 versus RBSN in PDAC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GAB1→partner) and Y-score (partner→GAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RBSN →	+0.275	+0.427	<.001	<.001	3	7
CCRCC	MYO1D →	+0.400	+0.470	<.001	<.001	3	6
LUAD	DDX21_S89 →	-0.815	-0.562	<.001	<.001	3	6
BRCA	DNAJA1_S335 →	-0.614	-0.500	<.001	<.001	3	6
BRCA	TRIM3 →	+0.360	+0.647	.008	.001	3	6
BRCA	PRKG1 →	+0.528	+0.750	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,994 associations by consensus.

GAB1 vs RBSN — PDAC

Explore this scatter interactively →