G6PC3

Across TCGA patient cohorts, G6PC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,944 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible G6PC3-associated proteins across cancer lineages are PSME3, DHX8, and ARPC3. Each is linked with G6PC3 in more than 6 cancer types. Because this analysis shows association rather than direction, both G6PC3-to-partner and partner-to-G6PC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, G6PC3 versus PSME3 in OV, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (G6PC3→partner) and Y-score (partner→G6PC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PSME3 →	+0.345	+0.519	<.001	<.001	2	7
LSCC	DHX8 →	+0.288	+0.491	<.001	<.001	3	5
BRCA	ARPC3 →	-0.265	-0.531	<.001	<.001	3	4
HNSC	ARPC5L →	-0.324	-0.484	<.001	.002	3	4
UCEC	STK17B →	-0.347	-0.383	.001	<.001	3	4
BRCA	ACTR3 →	-0.219	-0.548	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,944 associations by consensus.

G6PC3 vs PSME3 — OV

Explore this scatter interactively →