G6PC3

Across TCGA patient cohorts, G6PC3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,893 significant associations in total. GBM shows the largest number of these associations.

The most reproducible G6PC3-associated genes across cancer lineages are CCNJ, EDRF1, and MASTL. Each is linked with G6PC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both G6PC3-to-partner and partner-to-G6PC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, G6PC3 versus CCNJ in COAD, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (G6PC3→partner) and Y-score (partner→G6PC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CCNJ →	-0.420	-0.213	.007	.004	3	3
COAD	EDRF1 →	-0.479	-0.308	<.001	.005	3	3
BRCA	MASTL →	-0.670	-0.564	<.001	<.001	3	3
GBM	ATP8A1 →	-1.099	-0.243	<.001	<.001	3	3
GBM	LCOR →	-0.398	-0.273	<.001	<.001	3	3
GBM	MARCHF5 →	-0.435	-0.274	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,893 associations by consensus.

G6PC3 vs CCNJ — COAD

Explore this scatter interactively →