G6PC3

Across TCGA patient cohorts, G6PC3 protein abundance is significantly associated with the protein abundance of many other proteins, with 18,337 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible G6PC3-associated proteins across cancer lineages are MOGS, OGT, and PIGS. Each is linked with G6PC3 in more than 4 cancer types. Because this analysis shows association rather than direction, both G6PC3-to-partner and partner-to-G6PC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, G6PC3 versus MOGS in PDAC, with a Pearson correlation of 0.59.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (G6PC3→partner) and Y-score (partner→G6PC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MOGS →	+0.481	+1.002	<.001	<.001	3	5
GBM	OGT →	-0.220	-0.318	<.001	<.001	3	5
UCEC	PIGS →	+0.544	+0.752	<.001	<.001	3	5
UCEC	EMC1 →	+0.357	+0.547	<.001	<.001	3	5
PDAC	RPS12 →	-0.437	-0.637	<.001	<.001	3	4
UCEC	UNC93B1 →	+0.611	+0.403	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,337 associations by consensus.

G6PC3 vs MOGS — PDAC

Explore this scatter interactively →