G6PC2

Across TCGA patient cohorts, G6PC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,184 significant associations in total. GBM shows the largest number of these associations.

The most reproducible G6PC2-associated proteins across cancer lineages are TSHZ1_T852, DDAH1, and AKAP12_S612. Each is linked with G6PC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both G6PC2-to-partner and partner-to-G6PC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, G6PC2 versus TSHZ1_T852 in OV, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (G6PC2→partner) and Y-score (partner→G6PC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TSHZ1_T852 →	+0.889	+0.020	.002	.003	3	5
CCRCC	DDAH1 →	+0.543	+0.466	<.001	<.001	3	4
BRCA	AKAP12_S612 →	+0.740	+0.140	.002	.002	3	4
PDAC	RPS2 →	-0.242	-1.434	.001	.002	3	3
GBM	S100A11 →	-0.474	-0.454	.001	.001	3	3
PDAC	ITGB4_T1530 →	-0.978	-1.689	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,184 associations by consensus.

G6PC2 vs TSHZ1_T852 — OV

Explore this scatter interactively →