G6PC2

Across TCGA cell cohorts, G6PC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 591 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible G6PC2-associated GO terms across cancer lineages are Fatty acid oxidation, Sterol transport, and Negative regulation of neurotransmitter uptake. Each is linked with G6PC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both G6PC2-to-partner and partner-to-G6PC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid oxidation grouped by G6PC2-low versus G6PC2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (G6PC2→partner) and Y-score (partner→G6PC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Fatty acid oxidation →	+0.051	+0.007	.004	.009	3	4
SKIN	Sterol transport →	+0.060	+0.027	<.001	.009	3	4
SKIN	Negative regulation of neurotransmitter uptake →	+0.346	+0.029	.005	<.001	3	4
SKIN	Negative regulation of serotonin uptake →	+0.346	+0.029	.005	<.001	3	4
SKIN	Amino sugar metabolic process →	+0.050	+0.025	.007	.001	3	3
SKIN	Acrosomal vesicle exocytosis →	+0.740	+0.030	.004	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 591 associations by consensus.

Fatty acid oxidation by G6PC2 expression — PANCREAS

Explore this box plot interactively →