G3BP2

Across TCGA patient cohorts, G3BP2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,395 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible G3BP2-associated genes across cancer lineages are SDAD1, GRSF1, and CCNA2. Each is linked with G3BP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both G3BP2-to-partner and partner-to-G3BP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, G3BP2 versus SDAD1 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (G3BP2→partner) and Y-score (partner→G3BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SDAD1 →	+0.568	+0.258	.003	<.001	3	7
LUAD	GRSF1 →	+0.485	+0.243	<.001	<.001	3	7
BRCA	CCNA2 →	+0.860	+0.185	<.001	<.001	3	6
GBM	NPM1P9 →	+0.614	+0.195	<.001	.002	3	5
UCEC	PLK4 →	+0.783	+0.171	<.001	.001	2	6
UCEC	MAD2L1 →	+0.794	+0.149	.001	.008	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,395 associations by consensus.

G3BP2 vs SDAD1 — HNSC

Explore this scatter interactively →