G3BP2

Across TCGA cell cohorts, G3BP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,436 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible G3BP2-associated GO terms across cancer lineages are Ribosomal large subunit export from nucleus, Regulation of chromosome condensation, and CMP biosynthetic process. Each is linked with G3BP2 in more than 13 cancer types. Because this analysis shows association rather than direction, both G3BP2-to-partner and partner-to-G3BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit export from nucleus grouped by G3BP2-low versus G3BP2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (G3BP2→partner) and Y-score (partner→G3BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Ribosomal large subunit export from nucleus →	+0.103	+0.876	<.001	.001	3	14
SOFT_TISSUE	Regulation of chromosome condensation →	+0.169	+0.696	<.001	<.001	3	13
BREAST	CMP biosynthetic process →	+0.136	+0.819	<.001	<.001	3	13
BLOOD_Leukemia	Positive regulation of sterol biosynthetic process →	+0.107	+0.563	<.001	<.001	3	12
OVARY	Heterochromatin formation →	+0.070	+0.769	<.001	<.001	3	12
BLOOD_Leukemia	Positive regulation of cholesterol biosynthetic process →	+0.107	+0.563	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,436 associations by consensus.

Ribosomal large subunit export from nucleus by G3BP2 expression — OESOPHAGUS

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