FZD8

Across TCGA cell cohorts, FZD8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,528 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FZD8-associated GO terms across cancer lineages are Organelle transport along microtubule, Regulation of transepithelial transport, and Coronary artery morphogenesis. Each is linked with FZD8 in more than 6 cancer types. Because this analysis shows association rather than direction, both FZD8-to-partner and partner-to-FZD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle transport along microtubule grouped by FZD8-low versus FZD8-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD8→partner) and Y-score (partner→FZD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Organelle transport along microtubule →	+0.053	+1.142	.003	.001	3	7
PANCREAS	Regulation of transepithelial transport →	+0.065	+0.561	.009	.005	2	7
SKIN	Coronary artery morphogenesis →	+0.178	+1.834	<.001	<.001	3	6
URINARY_TRACT	Establishment of apical/basal cell polarity →	+0.158	+1.062	.006	.006	3	6
UPPER_AERODIGESTIVE_TRACT	Nucleoside triphosphate biosynthetic process →	+0.081	+1.036	.002	.001	3	6
SKIN	Endothelial cell migration →	+0.073	+0.993	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,528 associations by consensus.

Organelle transport along microtubule by FZD8 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →