FZD7

Across TCGA patient cohorts, FZD7 protein abundance is significantly associated with the protein abundance of many other proteins, with 10,560 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FZD7-associated proteins across cancer lineages are PTK7, TSPAN9, and LRRC15. Each is linked with FZD7 in more than 5 cancer types. Because this analysis shows association rather than direction, both FZD7-to-partner and partner-to-FZD7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD7 versus PTK7 in PDAC, with a Pearson correlation of 0.67.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD7→partner) and Y-score (partner→FZD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PTK7 →	+0.539	+0.759	<.001	<.001	3	6
BRCA	TSPAN9 →	+0.747	+1.150	.002	<.001	3	5
PDAC	LRRC15 →	+1.074	+0.869	<.001	<.001	3	5
PDAC	P3H3 →	+0.662	+0.993	<.001	<.001	3	5
HNSC	FAP →	+1.013	+1.016	<.001	<.001	3	5
OV	MAP1B_S1915 →	+1.353	+1.285	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,560 associations by consensus.

FZD7 vs PTK7 — PDAC

Explore this scatter interactively →