FZD6

Across TCGA patient cohorts, FZD6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,903 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FZD6-associated proteins across cancer lineages are FZD6_S653, STK3, and NUDCD1. Each is linked with FZD6 in more than 7 cancer types. Because this analysis shows association rather than direction, both FZD6-to-partner and partner-to-FZD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD6 versus FZD6_S653 in GBM, with a Pearson correlation of 0.87.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD6→partner) and Y-score (partner→FZD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FZD6_S653 →	+1.612	+1.733	<.001	<.001	3	8
LUAD	STK3 →	+0.411	+0.678	<.001	<.001	3	6
BRCA	NUDCD1 →	+0.389	+1.157	<.001	<.001	3	5
LUAD	PLCL2_S1113 →	-0.607	-0.407	<.001	.002	2	6
LUAD	SCRIB →	+0.285	+0.611	<.001	<.001	3	5
LSCC	IL16 →	-0.397	-0.673	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,903 associations by consensus.

FZD6 vs FZD6_S653 — GBM

Explore this scatter interactively →