FZD6

Across TCGA patient cohorts, FZD6 protein abundance is significantly associated with the RNA expression of many other genes, with 8,726 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FZD6-associated genes across cancer lineages are ITM2A, CD79B, and SLAMF1. Each is linked with FZD6 in more than 6 cancer types. Because this analysis shows association rather than direction, both FZD6-to-partner and partner-to-FZD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD6 versus ITM2A in HNSC, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD6→partner) and Y-score (partner→FZD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ITM2A →	-1.142	-0.440	<.001	<.001	3	7
OV	CD79B →	-1.250	-0.513	.009	.003	2	7
LSCC	SLAMF1 →	-0.775	-0.480	<.001	<.001	3	5
UCEC	TRBV29-1 →	-0.982	-0.367	<.001	.002	3	5
PDAC	SPIB →	-1.152	-0.601	.005	.003	3	5
LUAD	PPP1R16B →	-0.708	-0.349	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,726 associations by consensus.

FZD6 vs ITM2A — HNSC

Explore this scatter interactively →