FZD5

Across TCGA patient cohorts, FZD5 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,534 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FZD5-associated proteins across cancer lineages are PLS1, PLEKHA6_S459, and PLEKHA6_S808. Each is linked with FZD5 in more than 4 cancer types. Because this analysis shows association rather than direction, both FZD5-to-partner and partner-to-FZD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD5 versus PLS1 in HNSC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD5→partner) and Y-score (partner→FZD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PLS1 →	+0.636	+0.643	<.001	.002	3	5
LSCC	PLEKHA6_S459 →	+0.973	+0.752	<.001	<.001	3	4
PDAC	PLEKHA6_S808 →	+0.600	+0.586	.003	.004	3	4
UCEC	CGN →	+0.489	+0.639	.001	.003	2	5
LSCC	TJP3_S112 →	+0.621	+0.638	.001	.001	3	4
UCEC	WFS1 →	-0.546	-0.661	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,534 associations by consensus.

FZD5 vs PLS1 — HNSC

Explore this scatter interactively →