FZD5

Across TCGA patient cohorts, FZD5 protein abundance is significantly associated with the RNA expression of many other genes, with 462 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FZD5-associated genes across cancer lineages are TMEM147, LAPTM4A-DT, and THAP12P2. Each is linked with FZD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FZD5-to-partner and partner-to-FZD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD5 versus TMEM147 in PDAC, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD5→partner) and Y-score (partner→FZD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TMEM147 →	-0.324	-0.179	.009	.004	3	1
PDAC	LAPTM4A-DT →	-0.431	-0.183	.001	.006	3	1
PDAC	THAP12P2 →	-0.115	-0.189	.001	.001	3	1
PDAC	LINC02473 →	-0.547	-0.201	.003	.006	3	1
PDAC	SMC1B →	-0.420	-0.210	.003	.001	3	1
LUAD	MSLN →	-2.395	-0.628	.009	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 462 associations by consensus.

FZD5 vs TMEM147 — PDAC

Explore this scatter interactively →