FZD5

Across TCGA cell cohorts, FZD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,145 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FZD5-associated GO terms across cancer lineages are Copper ion export, Regulation of brown fat cell differentiation, and Bone mineralization. Each is linked with FZD5 in more than 9 cancer types. Because this analysis shows association rather than direction, both FZD5-to-partner and partner-to-FZD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by FZD5-low versus FZD5-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD5→partner) and Y-score (partner→FZD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Copper ion export →	-0.222	-1.228	<.001	<.001	3	10
LARGE_INTESTINE	Regulation of brown fat cell differentiation →	+0.084	+1.094	<.001	<.001	3	9
OVARY	Bone mineralization →	+0.149	+1.379	<.001	<.001	3	9
STOMACH	Regulation of actin filament-based movement →	+0.183	+1.701	<.001	<.001	3	8
LIVER	Positive regulation of establishment of T cell polarity →	-0.238	-1.993	<.001	<.001	3	8
LIVER	Response to vasopressin →	+0.286	+1.781	.006	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,145 associations by consensus.

Copper ion export by FZD5 expression — LARGE_INTESTINE

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