FZD5

Across TCGA cell cohorts, FZD5 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FZD5-associated genes across cancer lineages are BANF2, SEPTIN14, and IFNW1. Each is linked with FZD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FZD5-to-partner and partner-to-FZD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BANF2 grouped by FZD5-low versus FZD5-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD5→partner) and Y-score (partner→FZD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	BANF2 →	+0.096	+5.643	<.001	.002	3	2
LARGE_INTESTINE	SEPTIN14 →	+0.009	+3.684	<.001	.006	3	1
LARGE_INTESTINE	IFNW1 →	+0.013	+4.054	<.001	.004	3	1
LARGE_INTESTINE	CCL13 →	+0.258	+4.437	<.001	.004	3	1
LARGE_INTESTINE	SPDYE4 →	+0.022	+4.437	<.001	.004	3	1
LARGE_INTESTINE	CLEC9A →	+0.009	+4.562	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

BANF2 by FZD5 expression — BLOOD_Lymphoma

Explore this box plot interactively →