FZD4

Across TCGA patient cohorts, FZD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,151 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FZD4-associated proteins across cancer lineages are LAMA4, PRKG1, and ERG_S81. Each is linked with FZD4 in more than 8 cancer types. Because this analysis shows association rather than direction, both FZD4-to-partner and partner-to-FZD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD4 versus LAMA4 in UCEC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD4→partner) and Y-score (partner→FZD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LAMA4 →	+0.614	+0.581	<.001	<.001	3	9
LSCC	PRKG1 →	+0.681	+0.791	<.001	<.001	3	8
BRCA	ERG_S81 →	+0.664	+0.968	<.001	<.001	3	8
COAD	FERMT2 →	+0.704	+0.609	<.001	<.001	3	8
BRCA	HSPA12B →	+0.645	+1.051	<.001	<.001	3	8
BRCA	HSPG2 →	+0.492	+0.894	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,151 associations by consensus.

FZD4 vs LAMA4 — UCEC

Explore this scatter interactively →