FZD4

Across TCGA patient cohorts, FZD4 protein abundance is significantly associated with the RNA expression of many other genes, with 718 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FZD4-associated genes across cancer lineages are RPL36AP13, CD40, and UBL4A. Each is linked with FZD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FZD4-to-partner and partner-to-FZD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD4 versus RPL36AP13 in LSCC, with a Pearson correlation of -0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD4→partner) and Y-score (partner→FZD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPL36AP13 →	-0.752	-0.617	.004	.008	3	2
LSCC	CD40 →	-1.172	-0.910	<.001	.001	3	1
LSCC	UBL4A →	-0.855	-0.867	.001	.005	3	1
LSCC	TSC2 →	-0.859	-0.947	.001	.001	3	1
LSCC	TFPT →	-0.383	-0.623	.009	.008	3	1
LSCC	CNTNAP1 →	-1.235	-1.029	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 718 associations by consensus.

FZD4 vs RPL36AP13 — LSCC

Explore this scatter interactively →