FZD2

Across TCGA patient cohorts, FZD2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,037 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FZD2-associated genes across cancer lineages are MPP2, TMEM121, and FIRRE. Each is linked with FZD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FZD2-to-partner and partner-to-FZD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD2 versus MPP2 in LSCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD2→partner) and Y-score (partner→FZD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MPP2 →	+1.203	+0.808	.002	.003	3	2
UCEC	TMEM121 →	+1.100	+0.254	.007	.003	3	2
PDAC	FIRRE →	+1.051	+1.123	.001	.001	3	2
LSCC	SRRD →	+0.635	+0.682	.001	.007	3	1
LSCC	SRP54 →	+0.636	+0.813	.006	.004	3	1
LSCC	SEC23A →	+0.901	+0.766	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,037 associations by consensus.

FZD2 vs MPP2 — LSCC

Explore this scatter interactively →