FZD10

Across TCGA pan-cancer cohorts, FZD10 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated FZD10 data layer compared with 6 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FZD10 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FZD10 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

UCEC, ACC, and KIRP are the cancer types where FZD10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.858	0.571	<.001	104	view →
ACC	DFS	Median	All	0.252	0.659	<.001	57	view →
KIRP	OS	Quartile	All	0.858	0.972	.005	40	view →
THCA	OS	Median	III,IV	0.763	1.000	.005	39	view →
GBM	OS	Median	All	0.535	0.283	.001	20	view →
KIRC	DFS	Median	All	0.476	0.763	<.001	18	view →
STAD	OS	Quartile	IV	0.822	0.255	.002	15	view →
UCS	DFS	Median	II,III,IV	0.579	0.300	.024	12	view →
MESO	DFS	Quartile	IV	0.550	0.094	.006	12	view →
LGG	OS	Tertile	All	0.860	0.933	.004	10	view →
READ	DFS	Quartile	IV	0.851	0.363	.011	10	view →
DLBC	DFS	Median	IV	1.000	0.281	.005	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

FZD10–UCEC (OS)

Open the UCEC breakdown →